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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe6eff887bb9e7e4138509ca2d1e1afb7879c3dfac08e5059d0579098e5cd03' 
  AND token = 'I10JYvZ0zdT5GC3ixPMuPSj50wipnh2r0C4MKRvCIj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}