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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ec9dcc0a147f0e9e33469de4a262bc904b03bc859e4cdc6e10b33095c670b7d' 
  AND token = 'li1f/MtLpTKIXQB6U575KeXxGxiO6BRW8gieN7FsOQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}