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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d9a7307f33016ffa49d3509bbe57a77872db4a3366a2737e545feb20394dcc' 
  AND token = 'UjVeN+TsNHph+omh/i/0TH4AUZ++n0nwK4Avpc1eP4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}