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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074cf3165ed72f4d0c4638317fe1565e4dd1f5605e5b35dcb1d47bc3e52583ed' 
  AND token = 'qlRlknyx5A+AA+8N+iZAN5CdjHH6VhYCe1k3S1HYCic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}