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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa9efd3dbd39e14771d6af8baf65a0ef59fd3294fdcc623975d573d395aa23ee' 
  AND token = 'EsRCdNHP0vAP4nDkzw6gj5jTTuo+YrivHoyDW/NSzcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}