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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03df4d932ee4a01a0ce87847569cf3ac11722f594ca829d4226d8a3b899dc4c' 
  AND token = 'WLP9W+MEtQ9g1eryzhSvhBXHgS6NGCE5zrBz69PPjLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}