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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d9e5da762ac5a740bf26d4e75f165c2d7dbff27003d6d867815a26b2fb7e814' 
  AND token = 'ZbTMOFagf8YRr8h5c7rnQmt7BnesoGrNdS20H0FdBa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}