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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46fbb4c27cce31eddb60ff03500fa79d7bfa67840a44ce4f13736b7411a4861' 
  AND token = '+o1UhWRfHjb6wHkTcQCYVA4iQjxwR6JSayUALsSEvaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}