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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e01b64871eb051c4c8ed391625ed7f9ae5e2ad441c5d32b70e42cb66b31015d' 
  AND token = 'Oru86PTgPEG/dFBzCZrbhXmJ6Hwyp4bWUJSf+xl0JSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}