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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1db7bbdb48890ead50320f9ab0e585f1c4f07773b2d130dda6da5a8742491b4' 
  AND token = 'r1D21C1Hn2l4GO1tCkxOun1Gxquo65v1WXm2/yAeXRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}