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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de307dde585bd1a06fbb0e077f6c2da4a8504098874e4e52a7048d19945c2d44' 
  AND token = 'QXYHtDJb+a7y2xM/1Fvs5fFkw9LQcVlsoTtOXvHzGjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}