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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a77a8469f8de274428828d70127c234e7a1f56019311cbf82943895f928e0d' 
  AND token = 'PkQ3gWcfYV3VL9N/Sr/YIS2C41wMSFKiFpNFe33Imkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}