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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eefed2b64acf36b13d2b6ba73eef2ed226494831473c4c3340a77f97d0388f45' 
  AND token = 'U6aikw6tAvLhl+lFtABEq90YQ8SBYh991OsfUxR9nk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}