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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a3854ed9de56fbd6f6bdee8bf9f86ce3bbd4c494a3529758c5b48912b679de' 
  AND token = '44sr3Vlc/1n9eOHU8hC2AHcnbEfSraBMiK1oUc8NyHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}