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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0335a44b35b191c72773bbef3291d51bc54cc3aff62fdd7c0a240b595d602b6b' 
  AND token = 'vIVKYtFI+Opi1uIx0xnMUdI03cxUUU29yXnArcipUjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}