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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5085d46533cc87685ecc107bb76fc0374060de2846c50451b11a1b94a72d2ca5' 
  AND token = 'FeFE5V29W3/1o8aga/8TLmoDSkIvLyezUdZJtrY8CzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}