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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b946d0ecf5ed3fdad66a5308eddd8932bba61c1049ce1c685316a22a880d8280' 
  AND token = 'Sp9BBind0un0m53RTh7dY5wRNFh/x/AxDtSq4EnJiB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}