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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efe5508ebeebd9a75e2827ef3e5102726533f071d1f04e6cbd0b6f6dedc86401' 
  AND token = '11YUQyLmEVCNsVXQ21JF5/UYljFqK5RDg096xC1HTes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}