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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e872118e87b9584964da831bc38f8a0a075baec2dd48e5d8edb4c01342426f2' 
  AND token = 'C6W16xKxVfX4z8SziYPNEWGC78vwgBA1MvVHRYOj2WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}