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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4328747b83a9ee315df9afda56ccefc8c6a24b1d4f532ab3bdda53425a44e838' 
  AND token = 'qSYJnVmTwNRbTEpSm6iJxSY+a2cskMSxXGLzgTzuJWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}