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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546cc38e2bb2c764a9d979603d92bc7b36a0ee7b0de4a8b065f75164c407b705' 
  AND token = 'j4szk2TWRikD9Ccc/ZFZBbzYlFW6+hyVStu662sA7UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}