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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be4486f60160dddc58ee77fa381da1d90d1a13193c15c6dce1b8a6e51464327' 
  AND token = '6+nMAr3Jl9UqMuIQGOZUS3gWouKNX6TPiplDqKBIMxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}