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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99b42a29a598f98669c6980326d3d22aedc49bb1ee993c413be6cb7c64e6208a' 
  AND token = '/CeQViIM83jBoGpaceuXutZ5X4DvbCUent/HxWWaskw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}