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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110a26e62c5b3395edc5615586b71a63985576bc90df4f0a21bde545f02af2d4' 
  AND token = 'ecO55f3SU7Q1bzsg+ugr0DWidvOgmodDrx/snBPmO5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}