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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c729e2e644dccf018dee85ddd48af8ea38d4e863342ad1deac8a8ece69a8e35c' 
  AND token = '4KZf0O7cWa42vwpAY7yL5Vsf555Y0pjHYeBXqUXpIHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}