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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af915e79dec7d9cf80f3486dbf001d1a3a9ef26cc5949aa303a487d483bc848c' 
  AND token = 'hk/FbiaCok4ILeZsTv9ayNtQ7q0RZq6017MqMbxATyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}