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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa13226cb0675a17d474f1952b57761f36ba2d65b8b0e1d1b835b9ecaa04e7a' 
  AND token = 'vvX+bKQSMdPNheEhmgB9NUP+UBxvSO7R7p5xmQaRFMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}