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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d811311b74f61de98dfaa10b71dcf2c737539b2d2141c2c974e2bfde19daa98' 
  AND token = 'rc7n/DFoPCuGyRSdqbmF78hWj4GgblqngNtA6EOaNqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}