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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d6be38dd61559e3182cdbb9aac3ec68a28bb883b83a9bb463391b7c151565d4' 
  AND token = 'vElEk+V7jZTcXvc3iWHRK20k7tsyOeVNiBIU6ZVT878=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}