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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738abe443f321b091dfd0b1cd747db50348a6681e04dc5164b042d35af1de8b6' 
  AND token = 'iaFJButDXOD0KGbpgMjyT5eYh1hIcFCis+uzqNzsmOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}