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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd5186c2a7479e08c63773b866fd90414e3d9a24e9a1f26f7a1dcfe916a12599' 
  AND token = 'WTQQLnZuGB3GNg5o3d3Fe2GVGNB7IempRVUM0UZRxb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}