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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af79be04c94f270c62079c8c5ff61d6e30b1539d57c65ae58e84180963d0ce7' 
  AND token = '8ZMjrLbpnIXoj5hf3NAjBHZ0N+FLCMsrCcEuBYdM2H8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}