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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c0c9d65279080976d603bb797ff5152b7f4d95f8b9e5b457fec7c3b0a01b48' 
  AND token = 'ArBEclL/++FTOTm50mhWwcqPo+DN4i7oSnS5W/4QwqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}