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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0123090bb4199e9c62dc6d8943272ca47f56a3520e64202d6a038c422e2c44d3' 
  AND token = '+20/BsOy4aehlsl6mteRdT6+tNSAcGzTHLO2TxCsiks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}