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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60a077a32d7c4402b952bdfa38c2e9dc7880b3d0dc75a705992238e722b4c74' 
  AND token = 'D7lqqiMrX7p8lHf8oZb2XVpttD80n7GsJfPdCY0IK4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}