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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb212ff1a1916f69678bb160fc180498c2ed6e517167c70cd5dfeca650281ca3' 
  AND token = 'B5sKx1t3JcSb/JooHKgiL0XmEnRfPcZ+QKQ/t5gs2Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}