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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4876a9459d7ab334fc3b73d23342543de2357820d73e57a8ce6a12363aa2dd90' 
  AND token = '5ZmESLyiK+I7yAYOjqYWeZuXW0tb0yr6e33xDgFlA04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}