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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277de40af722ccccef07ee92198c7dc9f73c36cae53f90d1ae1e09e386d96977' 
  AND token = 'no0Nyu5BDhTGoFqj9CT7zPIngZWM+5znjqxoTJMT9+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}