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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18beb1aec8c2f72852355a2686c160fc37bf03dbe83947677a3d8b5cf635e6b2' 
  AND token = '35LkxMg12asmjdhIqFhNmNMsigMYd7XhJv6Itd3g/2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}