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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7693641c53b41c923233bb884aa6e7b5918164a9e242a229e304300347ea0216' 
  AND token = '1hZ/kuUPsh2FNqExjaZ1FZTcLlhfLD0TTEQFHv9AggU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}