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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59bf3b8b8e5bad75195fa6de1f0483783d3abfcf01f551c3d1feeb72feaae2a2' 
  AND token = 'WqZmlyRFDmuQVcKM6K509zxk95SF0pEJ38H8dXjWCUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}