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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aefdf0ff43bc6da3c79b66ae18f2ada904453ec13ac7c0f4cec74c2f2279418a' 
  AND token = 'yUwUM8qAj3sA0tWb4jD2STC2Z3iEeJL21QqGVKkxoNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}