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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6247a44df5e504d2b74659824c7a3b929bfe1741b21cc6de416d85d5f8a129e0' 
  AND token = 'D5/XbZCdXYx4mGa9Jyv7A57BdR9VjXpDaGy60N2TaP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}