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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a720f036d3b8c97e407e3053c229db16b68525d6396d78992abd8ca695383a27' 
  AND token = 'oFPI3Zpy79Kro5CGnZxmyE4WTnAFfzh9doG6xPKkLVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}