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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3742813f0cc276c7d978a4387ffbfe8b30f9e491b7d7506ab443dd049aa7a899' 
  AND token = 'fu/vGJ0e4m2LkiC/DB245rGrPAY07yzrme1jdiQswOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}