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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529f4e6ab0861cf0cbfcf8e548f34b01140dfee1441fa848eb55ad56b5a27b41' 
  AND token = 'NBwePbIcM5YskmuajhEgFtqSlXzhu5YZ96NTz32aq/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}