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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '664e38e855b1dafa9bc263572a3b96e37728d6697b7253d31cf0d3d06fc7d18e' 
  AND token = '2X7ZcZOw5cg/qLaoqbsw8IcYnvvVPwFkfOv8zRcBoiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}