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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '567281c99c3b561d686587ad39090aee102a8a5dc91abdf307a171cd721e05eb' 
  AND token = 'ekvQgWi6vI4//YJrttZcr5LN49/TZQD1wlvXC0LEO1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}