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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78816d6a7f97eebda31aec113fec767ed6c6e827c6518c4b9f38b59838fb9dc' 
  AND token = 'vDtOxeaRNeEZVk0UMMK0yPCIuA7BpEF5hV4PtVLvgK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}