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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f336ea863ab4926918909d35d6571428f1f964091165c51cff3d56d2b67e96ad' 
  AND token = 'tV61Nmx9PKFn50PFDwaF5dCLIsC8k7GpaUkV1Wgu1Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}